February QoM

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I heard that if I have Male Pattern Hair Loss and if I start using Rogaine (Minoxidil), I will have to use it forever? Is that true, and why?

 

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Yes this is true. The main reason for this is that there is no cure for Pattern Hair Loss. The underlying cause is a genetic disorder, and as such would require gene therapy, which does not exist. The medical therapies that exist, including Minoxidil, only reverse the effects of the genes and not the gene itself. Therefore, if you do not continue using the Minoxidil, you will lose the benefits of keeping the regrown hair.

September’s QOM- What is Aminexil?

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Hi Doc,

Could you give me some information on Aminexil Force R capsules? What is aminexil?

 

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Hiya!

Aminexil Force R is a relatively new topical hair loss product produced under the L’Oreal group. Aminexil,, 2,4-Diamino pyrimidine-3-oxide, is a derivative of Minoxidil.

Minoxidil

minoxidil

 

Amenixil

kopexil

 

It has been marketed as having the same positive effects as  Minoxidil, i.e. hair growth, without the side effects. It is also claimed to help prevent fibrosis or scarring around the hair follicles which can be seen in late stage Androgenetic Alopecia. There has only been a few studies done on the efficacy of this molecule. Therefore, it has not been rigorously examined when compared to Minoxidil.

Is it worth trying? Only if you have already exhausted available topical and oral options.

 

 

 

Male Pattern Hair Loss

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Male Pattern Hair Loss or Androgenetic Alopecia is the most common type of hair loss found in men. Up to 80% of men will experience some level of hair loss by their 70s. Most will discover their hair loss in their 30s and 40s however, quite a number may start long before in their teens.

So what causes Male Pattern Hair Loss?

Male Pattern Hair Loss is due to the activity of a hormone Dihydrotestosterone, a potent androgen (male hormone). The hair follicle in affected men is more sensitive to this hormone. There are several genes responsible for the condition and they can be inherited from either the mother, father, or both.   This hormone is made from Testosterone under the action of the enzyme, 5-alpha reductase. Dihydrotestosterone latches onto the receptors in the hair follicle and causes a decreased anagen (hair growth) along with  reduction in the size of the hair follicle. The hairs become progressively thinner and more vellus-like.

Stages of Male Pattern Hair Loss

There are several stages of Male Pattern Hair Loss.  The main staging system used is the Norwood Hamilton Scale for Hair Loss in men.

norwood-hamilton

Which stage do you fall under?

Next month: Treatment options

 

 

 

5 Myths about Hair Loss in Men

From time to time during my discussions with male patients, I come across general misconceptions about hair and hair loss. Some of this information may have been gathered from the internet or derived from basic folklore that has survived the test of time. These are some of the myths about hair loss in men that I’ve encountered.

1. Hair Loss is inherited from the mother

This is not true. The genes for hair loss are quite numerous and are inherited from both parents. The severity of your hair balding has more to do with the number of genes you inherited. If you have hair loss on both sides of your family, you are more likely to suffer from hair loss than a person who has no known family member with hair loss.

2. Only older men are affected

Though Male Pattern Hair Loss is seen in more middle-aged to elderly men, young men are also capable of being affected by the condition. A lot of men start as early as in their teen or early twenties.

3. If I take testosterone pills I will grow more hair

We all know that  testosterone is the predominant androgen (male) hormone that is responsible for the sexual characteristics of men. So because of this, there is some belief that if I take more testosterone then it would make me more virile and youthful. Losing one’s hair is thought to make some men feel less youthful. Unfortunately, this myth needs to quit while it’s ahead. Testosterone is converted to the more potent Dihydrotesterone which is the hormone responsible for binding to the receptors in the hair follicle and causing the hair to miniaturise. Taking more testosterone just adds fuel to the fire.

 

4. Hard physical exercise decreases conversion of Testosterone to DHT

I’m not sure how this myth came about but this is so far from the truth. Testosterone is usually converted to the more potent Dihydrotestosterone in all men. Individuals with Male Pattern Hair Loss are more sensitive to DHT because of their genetics.  So technically speaking they may have the same level of DHT as another man, but because of their greater sensitivity of their hair follicles to the hormone DHT, they lose more hair. Yes, there have been studies indicating that extremely hard exercise may cause a decrease in testosterone and therefore should theoretically decrease DHT. However, for all the athletes who are hitting the gym for hours on end but yet are still balding, this belief should be shelved quickly. Usain Bolt anyone?

5. Men who are balding have more testosterone.

Most studies show that most men have the same levels of testosterone across the board. Its production generally slows a bit as you get older, hence why some men’s libido and energy decrease as they get older. Those men who have genetic hair loss are more susceptible to the effects of the hormone DHT than those who don’t suffer from the condition.

 

Dr. Llorenia Muir-Green is a practising dermatologist in Jamaica.  She graduated from the UWI, first obtaining a double major in Chemistry and Biochemistry. She then went on to pursue a career in Medicine. Having obtained her Medical degree from UWI, she went on to pursue postgraduate specialisation in Clinical Dermatology at Cardiff University, for which she got distinction.  She was a recipient of the 2013 Fellowship in Hair and Scalp Disorders at the University of British Columbia.  She is a member of the North American Hair Research Society, International Society of Hair Restoration Surgery,  Dermatology Association of Jamaica as well as an Associate Member of the Caribbean Dermatology Association. She currently works at the Dermatology Clinic at National Chest Hospital where she recently established a Hair Clinic.

 

November’s QOM- How can I tell if I am balding?

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Hi Doc, my girlfriend says that my hairline is receding. My hair feels different in that area but it doesn’t look like my hairline is going back like Lebron James.  How can I tell if I am balding? Help! I’m too young for this!

 

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Hi there!

I can understand you going into panic mode when your girlfriend told you that you may be balding. Truth is, no one who is young wants to acknowledge that he is losing his hair. Balding is for “old people” as I often hear my patients say. The truth is most of us do not notice our own hair loss, however persons who are around us are more likely to do so. So, if they do notice this then it is likely that you have lost a good percentage of your hair already.

The best way to tell if you’re losing your hair is to look at your old pictures. Is your hairline going more inward? Can you see the hair receding at your temples? Is there thinning noted to the crown of your scalp? Does the hair especially at the crown seem finer and soft like a baby’s hair? The latter description is often described in men with tightly coiled/kinky hair.

For  most black men, their hairline is straight across and can sometimes be low. Due to the curliness of the hair, it doesn’t become too obvious when the hair line starts to recede or the hair at the top of the scalp starts to thin out, unlike persons of other races. This is due to the styling preference of cutting the hair low. If the hair were allowed to grow out into a low afro, it would become a bit more easier to tell that the hair is thinning. Also, due to the 3-D volume created by curls, thinning is hidden well. Things start to get very obvious when the top of the scalp thins out significantly.

In your case, it is best to see a professional to get an opinion and see if there can be anything done to halt the hair loss.

 

 

 

Dr. Llorenia Muir-Green is a practising dermatologist in Jamaica. She has an avid interest in hair and scalp disorders.  She is a member of the Medical Association of Jamaica,  Dermatology Association of Jamaica and is an Associate Member of the Caribbean Dermatology Association. She was a recipient of the 2013 Fellowship in Hair and Scalp Disorders at the University of British Columbia.